Most people using cannabidiol (CBD) products are aware of their potential health benefits and therapeutic effects. But they do know how exactly the endocannabinoid system (ECS) works. Remember that hemp-derived cannabinoids like CBD and THC produce their physiological effects by influencing the ECS. However, everything is not understood about the ECS or all of CBD’s effects on this system. Despite this, people are using cannabidiol-infused products for treating the symptoms of many common day ailments. In this article, we will discuss in detail how CBD and the endocannabinoid system cooperate.
The Useful Hemp Plant
Legally available CBD-infused health and wellness products are formulated using the extracts of hemp plant strains with a maximum of 0.3% THC; manufacturers use cannabidiol-rich parts like leaves, buds, and flowers for producing CBD hemp extract. This is to ensure that they will not produce mind-altering effects when you ingest them. Besides, a lot of research is conducted for understanding how cannabidiol works at the cellular level so that it can be used as part of the conventional treatment. It is generally believed that CBD uses are due to its positive effect on the ECS.
The Endocannabinoid System
The human body is like an assembly of multiple biological systems that work together; this keeps you healthy and fit. Some of these systems are the endocannabinoid system, nervous system (ECS), endocrine system, etc. Although not many people know, the ECS plays a key role in regulating the internal equilibrium of the body, i.e., it helps to keep other systems in balance.
Research has shown that endocannabinoid receptors are found throughout the body. The two main receptors of the ECS are CB1 and CB2; the former is part of the central and peripheral nervous systems, and the latter is associated with the immune system. For example, they are found in the skin, brain, bones, blood vessels, muscles, immune system, liver, and gut.
Listed below are some of the important regulating functions of the ECS:
- Immune system
- Pain perception
- Sleep-wake cycle
The Working Of CBD And The Endocannabinoid System
CBD interacts mainly with the CB2 receptors of the ECS. This can be one of the reasons for its analgesic, anti-inflammatory, and antiemetic effects. Also, it has an antagonistic effect on the CB1 receptors; this reduces the receptor’s affinity for THC, which helps to reduce the severity of THC’s adverse effects. Furthermore, cannabidiol increases serotonin levels in the brain by activating the serotonin receptors.
We hope that the details shared above clarified your doubts on how cannabidiol (CBD) and the endocannabinoid system cooperate.